Highlights
- The study evaluated healing effects of semisynthetic sodium alginate hydrogel alone and with PRP on corneal injuries in rats.
- PRP and hydrogel together led to the greatest epithelial thickness and minimal necrosis, indicating improved healing.
- Negative correlation found between tissue MMP-9 levels and corneal solidity, highlighting MMP-9's role in corneal healing.
- Hydrogel alone didn't significantly improve wound healing, but with PRP, it accelerated epithelial closure and neovascularization.
- New parameters for corneal wound healing assessment introduced via anterior segment optical coherence tomography processing.
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