Use of autologous platelet-rich plasma in the treatment of chronic anal fissures: a case series

Use of autologous platelet-rich plasma in the treatment of chronic anal fissures: a case series

Summary

Introduction . Chronic anal fissure is one of the most common and debilitating proctological pathologies. Its therapeutic management is complicated in patients with recurrent or high risk of anal incontinence.

Objective : To evaluate the effectiveness of autologous platelet-rich plasma infiltration to achieve healing of chronic anal fissures.

Materials and methods. A retrospective, descriptive, observational study was conducted in 16 patients treated with autologous platelet-rich plasma at our center for chronic anal fissures.

Results . The outcome was satisfactory in all patients, with proctalgia decreasing or disappearing within the first 48 hours in 94% of cases, and at one month after treatment, the fissure had healed in 89% of patients. Limitations: This study was limited by the small sample size. Furthermore, long-term follow-up was not reported.

Conclusion : The use of autologous platelet-rich plasma can be considered an alternative for the medical treatment of anal fissures, with good results, especially the resolution of proctalgia within the first 48 hours.

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